Ontology highlight
ABSTRACT:
SUBMITTER: Solger F
PROVIDER: S-EPMC7235507 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in cellular and infection microbiology 20200512
Obligate human pathogenic <i>Neisseria gonorrhoeae</i> are the second most frequent bacterial cause of sexually transmitted diseases. These bacteria invade different mucosal tissues and occasionally disseminate into the bloodstream. Invasion into epithelial cells requires the activation of host cell receptors by the formation of ceramide-rich platforms. Here, we investigated the role of sphingosine in the invasion and intracellular survival of gonococci. Sphingosine exhibited an anti-gonococcal ...[more]