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Right ventricular dyssynchrony: from load-independent right ventricular function to wall stress in severe pulmonary arterial hypertension.

ABSTRACT: Right ventricular (RV) dyssynchrony has been related to outcome in pulmonary arterial hypertension. Prospectively, we performed echocardiography with measurement of right ventricular dyssynchrony and pressure-volume loop catheterization in 27 pulmonary arterial hypertension patients. Afterload and diastolic function emerged as determinates of wall stress, which results in dyssynchrony.

SUBMITTER: Richter MJ 

PROVIDER: S-EPMC7235672 | biostudies-literature | 2020 Apr-Jun

REPOSITORIES: biostudies-literature

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Right ventricular dyssynchrony: from load-independent right ventricular function to wall stress in severe pulmonary arterial hypertension.

Richter Manuel J MJ   Badagliacca Roberto R   Wan Jun J   Vanderpool Rebecca R   Dalmer Antonia A   Ghofrani Hossein A HA   Harth Sebastian S   Seeger Werner W   Gall Henning H   Naeije Robert R   Tello Khodr K  

Pulmonary circulation 20200401 2

Right ventricular (RV) dyssynchrony has been related to outcome in pulmonary arterial hypertension. Prospectively, we performed echocardiography with measurement of right ventricular dyssynchrony and pressure-volume loop catheterization in 27 pulmonary arterial hypertension patients. Afterload and diastolic function emerged as determinates of wall stress, which results in dyssynchrony. ...[more]

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