Ontology highlight
ABSTRACT:
SUBMITTER: Hailstone M
PROVIDER: S-EPMC7237217 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Hailstone Martin M Waithe Dominic D Samuels Tamsin J TJ Yang Lu L Costello Ita I Arava Yoav Y Robertson Elizabeth E Parton Richard M RM Davis Ilan I
eLife 20200519
A major challenge in cell and developmental biology is the automated identification and quantitation of cells in complex multilayered tissues. We developed CytoCensus: an easily deployed implementation of supervised machine learning that extends convenient 2D 'point-and-click' user training to 3D detection of cells in challenging datasets with ill-defined cell boundaries. In tests on such datasets, CytoCensus outperforms other freely available image analysis software in accuracy and speed of cel ...[more]