Ontology highlight
ABSTRACT:
SUBMITTER: Bautista M
PROVIDER: S-EPMC7237572 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Bautista Maricris M Krishnan Anand A
Frontiers in oncology 20200513
Accumulating evidence now indicates that peripheral nerves and solid tumors mutually support the growth of each other. Tumor-derived molecular cues guide nerve infiltration to the tumor milieu, while the tumor-infiltrating nerves provide molecular support to promote tumor growth and dissemination. In this mini-review, we discuss the unique roles of sympathetic and parasympathetic nerves in promoting tumor growth and metastasis. The contribution of adrenergic and cholinergic signals, the specific ...[more]