Imaging Chemical Kinetics of Radical Polymerization with an Ultrafast Coherent Raman Microscope.

ABSTRACT: Numerous mechanisms have been proposed for polymerization to provide qualitative and quantitative prediction of how monomers spatially and temporally arrange into the polymeric chains. However, less is known about this process at the molecular level because the ultrafast chemical reaction is inaccessible for any form of microscope so far. Here, to address this unmet challenge, a stimulated Raman scattering microscope based on collinear multiple beams (COMB-SRS) is demonstrated, which allows label-free molecular imaging of polymer synthesis in action at speed of 2000 frames per second. The field of view of the developed 2 kHz SRS microscope is 30 × 28 µm2 with 50 × 46 pixels and 7 µs dwell time. By catching up the speed of chemical reaction, COMB-SRS is able to quantitatively visualize the

SUBMITTER: Li H 

PROVIDER: S-EPMC7237838 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature