Ontology highlight
ABSTRACT:
SUBMITTER: Prochasson L
PROVIDER: S-EPMC7238105 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Pathogens (Basel, Switzerland) 20200415 4
Before the establishment of an adaptive immune response, retroviruses can be targeted by several cellular host factors at different stages of the viral replication cycle. This intrinsic immunity relies on a large diversity of antiviral processes. In the case of HTLV-1 infection, these active innate host defense mechanisms are debated. Among these mechanisms, we focused on an RNA decay pathway called nonsense-mediated mRNA decay (NMD), which can target multiple viral RNAs, including HTLV-1 unspli ...[more]