Interaction between behavioral inhibition and neural alcohol cue-reactivity in ADHD and alcohol use disorder.

ABSTRACT:

Rationale

Compared to the general population, adult Attention-Deficit / Hyperactivity Disorder (ADHD) is more prevalent in patients with Alcohol Use Disorder (AUD). Impaired behavioral inhibition is a common characteristic in both ADHD and AUD. Relapse risk is increased in patients with AUD and comorbid, untreated ADHD and in AUD patients with increased neural cue-reactivity.

Objectives

In this study, we examined the interaction between neural correlates of behavioral inhibition and alcohol cue-reactivity with a hybrid imaging task.

Methods

Out of 69 adult study participants, we included n = 49 in our final analyses: Individuals had a diagnosis of either AUD (n = 13), ADHD (n = 14) or both (n = 5), or were healthy controls (HC; n = 17). The functional magnetic resonan

SUBMITTER: Vollstadt-Klein S 

PROVIDER: S-EPMC7239811 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature