Dataset Information

Association of Ascending Aortic Dilatation and Long-term Endurance Exercise Among Older Masters-Level Athletes.

ABSTRACT:

Importance

Aortic dilatation is frequently encountered in clinical practice among aging endurance athletes, but the distribution of aortic sizes in this population is unknown. It is additionally uncertain whether this may represent aortic adaptation to long-term exercise, similar to the well-established process of ventricular remodeling.

Objective

To assess the prevalence of aortic dilatation among long-term masters-level male and female athletes with about 2 decades of exercise exposure.

Design, setting, and participants

This cross-sectional study evaluated aortic size in veteran endurance athletes. Masters-level rowers and runners aged 50 to 75 years were enrolled from competitive athletic events across the United States from February to October 2018. Analysis began January 2019.

Exposures

Long-term endurance exercise.

Main outcomes and measures

The primary outcome was aortic size at the sinuses of Valsalva and the ascending aorta, measured using transthoracic echocardiography in accordance with contemporary guidelines. Aortic dimensions were compared with age, sex, and body size-adjusted predictions from published nomograms, and z scores were calculated where applicable.

Results

Among 442 athletes (mean [SD] age,?61?[6] years; 267 men [60%]; 228 rowers [52%]; 214 runners [48%]), clinically relevant aortic dilatation, defined by a diameter at sinuses of Valsalva or ascending aorta of 40 mm or larger, was found in 21% (n?=?94) of all participants (83 men [31%] and 11 women [6%]). When compared with published nomograms, the distribution of measured aortic size displayed a rightward shift with a rightward tail (all P?Conclusions and relevanceClinically relevant aortic dilatation is common among aging endurance athletes, raising the possibility of vascular remodeling in response to long-term exercise. Longitudinal follow-up is warranted to establish corollary clinical outcomes in this population.

SUBMITTER: Churchill TW

PROVIDER: S-EPMC7240353 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Publications

Association of Ascending Aortic Dilatation and Long-term Endurance Exercise Among Older Masters-Level Athletes.

Churchill Timothy W TW Groezinger Erich E Kim Jonathan H JH Loomer Garrett G Guseh J Sawalla JS Wasfy Meagan M MM Isselbacher Eric M EM Lewis Gregory D GD Weiner Rory B RB Schmied Christian C Baggish Aaron L AL

JAMA cardiology 20200501 5

<h4>Importance</h4>Aortic dilatation is frequently encountered in clinical practice among aging endurance athletes, but the distribution of aortic sizes in this population is unknown. It is additionally uncertain whether this may represent aortic adaptation to long-term exercise, similar to the well-established process of ventricular remodeling.<h4>Objective</h4>To assess the prevalence of aortic dilatation among long-term masters-level male and female athletes with about 2 decades of exercise e ...[more]

PMID: 32101252

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Dataset Information

Association of Ascending Aortic Dilatation and Long-term Endurance Exercise Among Older Masters-Level Athletes.

Importance

Objective

Design, setting, and participants

Exposures

Main outcomes and measures

Results

Publications

Association of Ascending Aortic Dilatation and Long-term Endurance Exercise Among Older Masters-Level Athletes.

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