Ontology highlight
ABSTRACT:
SUBMITTER: Wu L
PROVIDER: S-EPMC7240859 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Wu Longxiang L Xiang Shiqi S Hu Xiheng X Mo Miao M Zhao Cheng C Cai Yi Y Tong Shiyu S Jiang Huichuan H Chen Linxiao L Wang Zhi Z Xiong Wei W Ou Zhenyu Z
Clinical and translational medicine 20200101 1
<h4>Background</h4>A high prevalence of osteoblastic bone metastases is characteristic of prostate cancer. Prostate-specific antigen (PSA) is a serine protease uniquely produced by prostate cancer cells and is an important serological marker for prostate cancer. However, whether PSA modulates the osteogenic process remains largely unknown. In this study, we explored the effect of PSA on modulating the osteoblastic differentiation of mesenchymal stem cells (MSCs). In this study, we used flow cyto ...[more]