Ontology highlight
ABSTRACT:
SUBMITTER: Nie L
PROVIDER: S-EPMC7241017 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Nie Lei L Deng Yaling Y Li Pei P Hou Ruixia R Shavandi Amin A Yang Shoufeng S
ACS omega 20200506 19
Fabrication of reinforced scaffolds for bone regeneration remains a significant challenge. The weak mechanical properties of the chitosan (CS)-based composite scaffold hindered its further application in clinic. Here, to obtain hydroxyethyl CS (HECS), some hydrogen bonds of CS were replaced by hydroxyethyl groups. Then, HECS-reinforced polyvinyl alcohol (PVA)/biphasic calcium phosphate (BCP) nanoparticle hydrogel was fabricated via cycled freeze-thawing followed by an <i>in vitro</i> biominerali ...[more]