Rapid glycemic regulation in poorly controlled patients living with diabetes, a new associated factor in the pathophysiology of Charcot's acute neuroarthropathy.
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ABSTRACT:
SUBMITTER: Dardari D
PROVIDER: S-EPMC7241699 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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Rapid glycemic regulation in poorly controlled patients living with diabetes, a new associated factor in the pathophysiology of Charcot's acute neuroarthropathy.
Dardari Dured D Van Georges Ha GH M'Bemba Jocelyne J Laborne Francois-Xavier FX Bourron Olivier O Davaine Jean Michel JM Phan Franck F Foufelle Fabienne F Jaisser Frédéric F Penfornis Alfred A Hartemann Agnes A
PloS one 20200521 5
<h4>Objective</h4>Aggressive antidiabetic therapy and rapid glycemic control are associated with diabetic neuropathy. Here we investigated if this is also the case for Charcot neuroarthropathy.<h4>Research design and methods</h4>HbA1c levels and other relevant data were extracted from medical databases of 44 cases of acute Charcot neuroarthropathy.<h4>Results</h4>HbA1c levels significantly declined from 8.25% (67mmol/mol) [7.1%-9.4%](54-79mmol/mol), at -6 months (M-6), to 7.40%(54mmol/mol) [6.70 ...[more]
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