Neuroprotection in Parkinson's disease: facts and hopes.
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ABSTRACT:
SUBMITTER: Salamon A
PROVIDER: S-EPMC7242234 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Neuroprotection in Parkinson's disease: facts and hopes.
Salamon András A Zádori Dénes D Szpisjak László L Klivényi Péter P Vécsei László L
Journal of neural transmission (Vienna, Austria : 1996) 20191211 5
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. Behind the symptoms there is a complex pathological mechanism which leads to a dopaminergic cell loss in the substantia nigra pars compacta. Despite the strong efforts, curative treatment has not been found yet. To prevent a further cell death, numerous molecules were tested in terms of neuroprotection in preclinical (in vitro, in vivo) and in clinical studies as well. The aim of this review article is to sum ...[more]
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