Neural networks for protein structure and function prediction and dynamic analysis.

ABSTRACT: Hardware and software advancements along with the accumulation of large amounts of data in recent years have together spurred a remarkable growth in the application of neural networks to various scientific fields. Machine learning based on neural networks with multiple (hidden) layers is becoming an extremely powerful approach for analyzing data. With the accumulation of large amounts of protein data such as structural and functional assay data, the effects of such approaches within the field of protein informatics are increasing. Here, we introduce our recent studies based on applications of neural networks for protein structure and function prediction and dynamic analysis involving: (i) inter-residue contact prediction based on a multiple sequence alignment (MSA) of amino acid sequences,

SUBMITTER: Tsuchiya Y 

PROVIDER: S-EPMC7242519 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature