Clinicopathologic Features and Outcome of Adenocarcinoma of the Anal Canal: A Population-Based Study.

ABSTRACT:

Background

Anal canal adenocarcinoma (AA) is an uncommon tumor of the gastrointestinal tract. We seek to provide a detailed description of the incidence, demographics, and outcome of this rare tumor in the United States.

Methods

The data on anal canal adenocarcinoma from SEER Program, between 1973-2015, were extracted. We analyzed the incidence rates by demographics and tumor characteristics, followed by analysis of its impact on survival.

Results

The incidence of AA increased initially by 4.03% yearly from 1973 to 1985 but had a modest decline of 0.32% annually thereafter. The mean age for diagnosis of AA was 68.12 ± 14.02 years. Males outnumbered females by 54.8 to 45.2%. Tumors were mostly localized on presentation (44.4%) and moderately differentiated (41.1%). Age

SUBMITTER: Gogna S 

PROVIDER: S-EPMC7243005 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature