Index of Microcirculatory Resistance Measured during Intracoronary Adenosine-Induced Hyperemia.

ABSTRACT:

Background

The index of microcirculatory resistance is an invasive measure of coronary microvascular function that has to be calculated during maximal hyperemia, classically achieved with intravenous adenosine (IV). The aim of this study was to evaluate the use of intracoronary (IC) adenosine for the calculation of IMR.

Methods and results

31 patients with stable coronary artery disease were included in the study. Coronary pressure and thermodilution measurements were obtained at rest and during maximal hyperemia using a pressure-temperature sensor-tipped coronary guidewire. Duplicate measurements were performed using first IC and then IV adenosine. Dispersion of transit times was comparable for IC and IV adenosine. IMR values based on IC vs IV adenosine showed a high level

SUBMITTER: Santos-Pardo I 

PROVIDER: S-EPMC7243016 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature