Dataset Information

UNaProd: A Universal Natural Product Database for Materia Medica of Iranian Traditional Medicine.

ABSTRACT: Background:Iranian traditional medicine (ITM) is a holistic medical system that uses a wide range of medicinal substances to treat disease. Reorganization and standardization of the data on ITM concepts is a necessity for optimal use of this rich source. In an initial step towards this goal, we created a database of ITM materia medica. Main Body. Primarily based on Makhzan al-Advieh, which is the most recent encyclopedia of materia medica in ITM with the largest number of monographs, a database of natural medicinal substances was created using both text mining methods and manual editing. UNaProd, a Universal Natural Product database for materia medica of ITM, is currently host to 2696 monographs, from herbal to animal to mineral compounds in 16 diverse attributes such as origin and scientific name. Currently, systems biology, and more precisely systems medicine and pharmacology, can be an aid in providing rationalizations for many traditional medicines and elucidating a great deal of knowledge they can offer to guide future research in medicine. Conclusions:A database of materia medica is a stepping stone in creating a systems pharmacology platform of ITM that encompasses the relationships between the drugs, their targets, and diseases. UNaProd is hyperlinked to IrGO and CMAUP databases for Mizaj and molecular features, respectively, and it is freely available at http://jafarilab.com/unaprod/.

SUBMITTER: Naghizadeh A

PROVIDER: S-EPMC7243028 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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UNaProd: A Universal Natural Product Database for <i>Materia Medica</i> of Iranian Traditional Medicine.

Naghizadeh Ayeh A Hamzeheian Donya D Akbari Shaghayegh S Mohammadi Fahimeh F Otoufat Tohid T Asgari Saeme S Zarei Azadeh A Noroozi Samane S Nasiri Najmeh N Salamat Mahdi M Karbalaei Reza R Mirzaie Mehdi M Rezaeizadeh Hossein H Karimi Mehrdad M Jafari Mohieddin M

Evidence-based complementary and alternative medicine : eCAM 20200513

<h4>Background</h4>Iranian traditional medicine (ITM) is a holistic medical system that uses a wide range of medicinal substances to treat disease. Reorganization and standardization of the data on ITM concepts is a necessity for optimal use of this rich source. In an initial step towards this goal, we created a database of ITM <i>materia medica</i>. <i>Main Body</i>. Primarily based on Makhzan al-Advieh, which is the most recent encyclopedia of <i>materia medica</i> in ITM with the largest numb ...[more]

PMID: 32454857

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Project description:This article provides the most updated dataset of Latin botanical identifications for the materia medica in Tibetan medicine, known as Bö Luk Sowa Rigpa (Tib. Bod lugs gso ba rig pa), or the "Tibetan knowledge field of healing," often denoted in English simply as Sowa Rigpa. As one of the major scholarly Asian traditional medical systems, Sowa Rigpa is the principal health resource for populations across Tibetan regions of China, Mongolia, Bhutan, Nepal, India, and culturally-related areas of Russia. The geography represented by this medicinal plant dataset extends across the entire Tibetan plateau, its adjacent ranges, the wider transregional Himalayas, central Asia and much of the Indian subcontinent. Data collection drew from textual analysis of the seminal works of the Tibetan medical canon, including the Four Medical Treatises, Crystal Orb and Rosary among others; as well as the contemporary definitive work Stainless Crystal Mirror of Materia Medica by Gawé Dorjé. Study authors applied the same classification system as Gawé Dorjé, yet reanalyzed specimens according to a database cataloging research on regional herbarium botanical specimens, geographic distributions and regional plant chemistry studies, and confirming proper identification with the most current modern botanical taxonomies. Subsequently, almost 700 of the most commonly used materia medica were selected for compilation. Thus, this dataset represents updated botanical identifications and confirmations from both early and contemporary sources. Botanical specimen names were entered into spreadsheet format with Gawé Dorjé's categories listed alongside Deumar Tendzin Püntsok's early standard. Enclosed raw data are written in Unicode Tibetan font to retain fidelity to entries in the classical texts, with parallel columns in standard Wylie Tibetan transliteration and phonetic transcription. Latin botanical names are updated for each materia medica specimen using Kew's Medicinal Plant Names Services (Kew-MPNS) with missing entries supplied by World Flora Online (WFO) and Flora of China (FoC). This dataset is the first publicly available comprehensive ethnobotanical identification of Sowa Rigpa materia medica with Latin binomial nomenclature. This dataset was developed to inform botanical and pharmacological analysis of the Tibetan medical materia medica repertoire as well as make comparative analyses of related materia medica in other Asian medical systems.

Dataset Information

UNaProd: A Universal Natural Product Database for Materia Medica of Iranian Traditional Medicine.

Publications

UNaProd: A Universal Natural Product Database for <i>Materia Medica</i> of Iranian Traditional Medicine.

Similar Datasets

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