Dataset Information

HisgAtlas 1.0: a human immunosuppression gene database.

ABSTRACT: Immunosuppression is body's state in which the activation or efficacy of immune system is weakened. It is associated with a wide spectrum of human diseases. In the last two decades, tremendous efforts have been made to elucidate the mechanism of hundreds of immunosuppression genes. Immunosuppression genes could be valuable drug targets or biomarkers for the immunotherapeutic treatment of different diseases. However, the information of all previously identified immunosuppression genes is dispersed in thousands of publications. Here, we provide the HisgAtlas database that collects 995 previously identified human immunosuppression genes using text mining and manual curation. We believe HisgAtlas will be a valuable resource to search human immunosuppression genes as well as to investigate their functions in further research. Database URL: http://biokb.ncpsb.org/HisgAtlas/.

SUBMITTER: Liu Y

PROVIDER: S-EPMC7243927 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature

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HisgAtlas 1.0: a human immunosuppression gene database.

Liu Yuan Y He Mengqi M Wang Dan D Diao Lihong L Diao Lihong L Liu Jinying J Tang Li L Guo Shuzhen S He Fuchu F Li Dong D

Database : the journal of biological databases and curation 20170101

Immunosuppression is body's state in which the activation or efficacy of immune system is weakened. It is associated with a wide spectrum of human diseases. In the last two decades, tremendous efforts have been made to elucidate the mechanism of hundreds of immunosuppression genes. Immunosuppression genes could be valuable drug targets or biomarkers for the immunotherapeutic treatment of different diseases. However, the information of all previously identified immunosuppression genes is disperse ...[more]

PMID: 31725860

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Project description:BackgroundConsidering the growing demand for plant trait data and taking into account the lack of trait data from Eastern Europe, especially from its steppic region, we launched a new Ukrainian Plant Trait Database (UkrTrait v. 1.0) aiming at collecting all the available plant trait data from Ukraine.To facilitate further use of this database, we linked the trait terminology to the TRY Plant Trait Database, Thesaurus of Plant Characteristics (TOP) and Plant Trait Ontology (TO). For taxa names, we provide the crosswalks between the Ukrainian checklist and international sources, i.e. GBIF Backbone Taxonomy, World Checklist of Vascular Plants (World Checklist of Vascular Plants (World Checklist of Vascular Plants (WCVP), World Flora Online (WFO) and Euro+Med PlantBase. We aim to integrate our data into the relevant global (TRY Plant Trait Database) and pan-European (FloraVeg.EU) databases. The current version of the database is freely available at the Zenodo repository and will be updated in the future.New informationUntil now, plant traits for the Ukrainian flora were scattered across literature, often focusing on single species and written mainly in Ukrainian. Additionally, many traits were in grey literature or remained non-digitised, which rendered them inaccessible to the global scientific community. Addressing this gap, our Ukrainian Plant Trait Database (UkrTrait v. 1.0) represents a significant step forward. We compiled and digitised plant traits from local Ukrainian literature sources. Furthermore, we performed our own field and laboratory measurements of various plant traits that were not previously available in literature. In the current version of the UkrTrait, we focus on vascular plant species that are absent from the other European trait databases, with emphasis on species that are representative for the steppe vegetation. Traits assembled from literature include life span (annuals, biennials, perennials), plant height, flowering period (flowering months), life form (by Raunkiaer), plant growth form and others. Our own measured traits include seed mass, seed shape, leaf area, leaf nitrogen concentration and leaf phosphorus concentration. The current version, i.e. UkrTrait v. 1.0, comprises digitised literature data of 287,948 records of 75 traits for 6,198 taxa and our own trait measurements of 2,390 records of 12 traits for 388 taxa.

Dataset Information

HisgAtlas 1.0: a human immunosuppression gene database.

Publications

HisgAtlas 1.0: a human immunosuppression gene database.

Similar Datasets

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