Lower Grade Gliomas.

ABSTRACT:

Purpose of review

Low-grade gliomas (LGG) are a group of primary brain tumors that arise from supporting glial cells. They are characterized by a mutation in the isocitrate dehydrogenase (IDH) enzyme and include astrocytomas and oligodendrogliomas. They usually affect young adults, and their main treatment consists of surgical resection, followed by radiation and chemotherapy in selected patients. This article reviews recent research on the clinical and molecular aspects of the disease and innovative therapeutic modalities in the process.

Recent findings

Newly identified clinical and molecular features are currently used in the classification of LGG and applied in treatment-planning decisions. Advanced studies on the cellular level have an advanced understanding of the metab

SUBMITTER: Youssef G 

PROVIDER: S-EPMC7244462 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature