Ontology highlight
ABSTRACT:
SUBMITTER: Fang Y
PROVIDER: S-EPMC7244897 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Fang Yuan Y Wu Xuemei X Li Lin L Zhu Jinhong J Wu Haiyan H Zhou Haixia H He Jing J Wang Yizhen Y
Bioscience reports 20200501 5
TP53 is a tumor suppressor gene that regulates cell growth, apoptosis and DNA repair. Previous studies have reported the contribution of TP53 Arg72Pro (rs1042522 C>G) polymorphism to pathogenesis of multiple tumors. Hence, we evaluated the association between this polymorphism and neuroblastoma susceptibility in eastern Chinese children. The Taqman genotyping assay was performed in 373 patients and 762 controls. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to assess the ...[more]