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The association between meaning in life and harmful drinking is mediated by individual differences in self-control and alcohol value.

ABSTRACT: Introduction:The adoption of adult roles that provide meaning in life is associated with reduced harmful drinking. The current study examined whether this relationship is mediated by increased self-control and reduced value of alcohol. Methods:Cross-sectional design. 1043 adults (786 females) ≥18 years old completed an online survey. The outcome variable was scores on the Alcohol Use Disorders Identification Test (AUDIT), predictor variables were presence of and search for meaning in life (Meaning in Life Questionnaire), and mediating variables were trait self-control (Brief Self-Control Scale) and the value of alcohol (Brief Assessment of Alcohol Demand). Results:Presence of meaning in life had a significant negative association (B = -0.01, SE = 0.00, 95% CI -0.02 to -0.00, p = .015), whilst search for meaning in life had a significant positive association (B = 0.01, SE = 0.00, 95% CI 0.01 to 0.02, p = .001) with AUDIT scores. The negative association was mediated by increased self-control (B = -0.09, SE = 0.01, 95% CI -0.12 to -0.06) and decreased value of alcohol (B = -0.02, SE = 0.01, 95% CI -0.04 to 0.00), whilst the positive association was mediated by decreased self-control (B = 0.05, SE = 0.01, 95% CI 0.03 to 0.07) and increased value of alcohol (B = 0.02, SE = 0.01, 95% CI 0.00 to 0.04), thereby supporting our hypotheses. Conclusions:The relationships between presence and search for meaning in life and harmful drinking are mediated by individual differences in both trait self-control and the value of alcohol.

SUBMITTER: Copeland A

PROVIDER: S-EPMC7244925 | biostudies-literature |

REPOSITORIES: biostudies-literature

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Project description:BackgroundMost physiological studies interested in alcohol-dependence examined ethanol as a pharmacological agent rather than a nutrient. We conducted two studies, which assessed the metabolic and endocrine factors involved in the regulation of alcohol and nutrient intake in alcohol-dependent (AD) subjects. We also examined the potential role of a disruption in energy balance in alcohol-dependence.Methods and resultsIn Study-1, quantitative dietetic interviews of eating and drinking habits were conducted with 97 AD subjects. The population was split around a median alcohol intake value of 12.5 kcal/kg/day. The results showed that the "low alcohol" drinking AD subjects had high Body Mass Index (BMI) and Fat Mass (FM) and alcohol intake was compensated for by a decrease in non-alcoholic intakes. "High alcohol" drinking AD subjects, on the other hand, had low BMI and FM and the total caloric intakes were largely above norms. In Study-2, 24 AD inpatients were submitted to dietetic interviews, calorimetry and blood samplings for the measurement of biomarkers of the regulation of metabolism and satiety, on day 2, 5 and 16 of abstinence. These patients were compared with 20 controls matched for age and gender. We observed in AD patients an increase in cortisol, leptin and PYY plasma levels and a decrease in ghrelin, which might explain the observed decrease in non-alcoholic intakes. However, alcoholic and non-alcoholic intakes correlated positively with basal metabolism and negatively with leptin and leptin/BMI.ConclusionFor individuals consuming below 12.5 kcal/kg/day of alcohol, alcohol intake is compensated for by a decrease in non-alcoholic nutrient intakes, probably due to changes in metabolic and satiety factors. For individuals consuming above 12.5 kcal/kg/day of alcohol, alcohol accelerates metabolism and decreases fat mass and leptin levels, and the total caloric intake largely exceeds norms. A dual model for regulation of energy intake in AD subjects is proposed.

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The association between meaning in life and harmful drinking is mediated by individual differences in self-control and alcohol value.

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