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Weight-for-age distributions among children with HIV on antiretroviral therapy in the International epidemiology Databases to Evaluate AIDS (IeDEA) multiregional consortium.


ABSTRACT: OBJECTIVE:Pediatric antiretroviral therapy (ART) for children with HIV (CHIV) must be dosed appropriately for children's changing weights as they grow. To inform accurate estimates of ART formulations and doses needed, we described weight-for-age distributions among CHIV on ART in the IeDEA global pediatric collaboration between 2004 and 2016, using data from six regions (East, West, Central, and Southern Africa, Asia-Pacific, and Central/South America and the Caribbean). RESULTS:Overall, 59,862 children contributed to the analysis. Age and weight data were available from 530,080 clinical encounters for girls and 537,894 for boys. For each one-year age stratum from 0 to 15 years, we calculated the proportion of children in each of the weight bands designated by the World Health Organization as relevant to pediatric ART formulations: 0 to ?

SUBMITTER: Jesson J 

PROVIDER: S-EPMC7245795 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Weight-for-age distributions among children with HIV on antiretroviral therapy in the International epidemiology Databases to Evaluate AIDS (IeDEA) multiregional consortium.

Jesson Julie J   Desmonde Sophie S   Yiannoutsos Constantin T CT   Patten Gabriela G   Malateste Karen K   Duda Stephany N SN   Kumarasamy Nagalingeswaran N   Yotebieng Marcel M   Davies Mary-Ann MA   Musick Beverly B   Leroy Valeriane V   Ciaranello Andrea A  

BMC research notes 20200524 1


<h4>Objective</h4>Pediatric antiretroviral therapy (ART) for children with HIV (CHIV) must be dosed appropriately for children's changing weights as they grow. To inform accurate estimates of ART formulations and doses needed, we described weight-for-age distributions among CHIV on ART in the IeDEA global pediatric collaboration between 2004 and 2016, using data from six regions (East, West, Central, and Southern Africa, Asia-Pacific, and Central/South America and the Caribbean).<h4>Results</h4>  ...[more]

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