Modeling Neurodegenerative Disorders in Drosophila melanogaster.
Ontology highlight
ABSTRACT:
SUBMITTER: Bolus H
PROVIDER: S-EPMC7246467 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Publications
Modeling Neurodegenerative Disorders in <i>Drosophila melanogaster</i>.
Bolus Harris H Crocker Kassi K Boekhoff-Falk Grace G Chtarbanova Stanislava S
International journal of molecular sciences 20200426 9
<i>Drosophila melanogaster</i> provides a powerful genetic model system in which to investigate the molecular mechanisms underlying neurodegenerative diseases. In this review, we discuss recent progress in <i>Drosophila</i> modeling Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis (ALS), Huntington's Disease, Ataxia Telangiectasia, and neurodegeneration related to mitochondrial dysfunction or traumatic brain injury. We close by discussing recent progress using <i>Drosophil ...[more]
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