Dataset Information

Relationship between the Condylion-Gonion-Menton Angle and Dentoalveolar Heights.

ABSTRACT: An accurate estimation of both facial growth and the dentoalveolar dimension is key to successful treatment. The aim of this study was to analyze the relation between the Condylion-Gonion-Menton angle (CoGoMe^) and dentoalveolar heights in a population of patients from southern Italy. This retrospective study analyzed 270 cephalograms of 115 males (42.1%, mean age 15.5 ± 5.2 years) and 155 females (57.9%, mean age 15.6 ± 5.9 years). The facial divergency was evaluated with the Sella-Nasion and Gonion-Gnation angle (SN^GoGn), mandibular structure with the CoGoMe^, and dentoalveolar heights were assessed in four measurements: upper anterior (UADH), lower anterior (LADH), upper posterior (UPDH), and lower posterior (LPDH). Data were analyzed by means of Pearson's correlation and linear regression model (p < 0.05). All the dentoalveolar heights were strongly correlated among them (p < 0.001). The UADH was correlated with the SN^GoGn (r = 0.145; p = 0.017), while the LPDH was correlated with the CoGoMe^ (r = -0.183; p = 0.003). Moreover, there was a positive association between the UADH and the SN^GoGn (B = 0.08; 95% CI: 0.014-0.144; p = 0.017), and a negative association between the CoGoMe^ and the LPDH (B = -0.098; 95% CI: -0.161-0.035; p = 0.003). Facial divergency and mandibular structure are associated with dentoalveolar heights.

SUBMITTER: Valletta R

PROVIDER: S-EPMC7246519 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Relationship between the Condylion-Gonion-Menton Angle and Dentoalveolar Heights.

Valletta Rosa R Rongo Roberto R Pango Madariaga Ada Carolina AC Baiano Roberta R Spagnuolo Gianrico G D'Antò Vincenzo V

International journal of environmental research and public health 20200509 9

An accurate estimation of both facial growth and the dentoalveolar dimension is key to successful treatment. The aim of this study was to analyze the relation between the Condylion-Gonion-Menton angle (CoGoMe^) and dentoalveolar heights in a population of patients from southern Italy. This retrospective study analyzed 270 cephalograms of 115 males (42.1%, mean age 15.5 ± 5.2 years) and 155 females (57.9%, mean age 15.6 ± 5.9 years). The facial divergency was evaluated with the Sella-Nasion and G ...[more]

PMID: 32397490

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Project description:PurposeTo determine whether 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) affect the risk of developing open-angle glaucoma (OAG) in persons with hyperlipidemia.DesignRetrospective, longitudinal cohort analysis.ParticipantsIndividuals aged ?60 years with hyperlipidemia enrolled in a national United States managed care network between 2001 and 2009.MethodsMultivariable Cox regression analyses were performed to assess the relationship between statin use and the development of OAG (from no prior OAG diagnosis), progression from a prior diagnosis of glaucoma suspect to a diagnosis of OAG, and need for medical or operative interventions for OAG. Regression models were adjusted for sociodemographic factors and medical and ocular comorbidities.Main outcome measuresHazard ratios (HRs) with 95% confidence intervals (CIs).ResultsOf the 524 109 individuals with hyperlipidemia, 316 182 (60%) had ?1 outpatient prescription for statins. The hazard of developing OAG decreased 0.3% (adjusted HR, 0.997; 95% CI 0.994-0.999) for every additional month of statin consumption. Individuals with hyperlipidemia who took statins continuously for 2 years had an 8% (adjusted HR, 0.922; 95% CI, 0.870-0.976) decreased OAG risk relative to those who received no statin therapy. The hazard of progressing from a diagnosis of glaucoma suspect to OAG decreased 0.4% (adjusted HR, 0.996; 95% CI, 0.993-0.999) for every additional month of statin exposure. Individuals who took statins continuously for 2 years had a 9% (adjusted HR, 0.907; 95% CI, 0.846-0.973) decreased risk of progressing from glaucoma suspect to OAG relative to those who received no statin therapy. The hazard of requiring medical treatment for OAG decreased 0.4% (adjusted HR, 0.996; 95% CI, 0.993-0.998) for every additional month of statin exposure. No differences in need for glaucoma surgery were noted among those with OAG who were and were not taking statins (adjusted HR, 1.002; 95% CI, 0.994-1.010).ConclusionsStatin use was associated with a significant reduction in the risk of OAG among persons with hyperlipidemia. Given the mounting evidence of statin protection against OAG including both basic science and observational clinical studies, an interventional prospective study might provide additional insights into the role of statins in the prevention of early OAG.

Project description:T1 sagittal angle has been reported to be used as a parameter for assessing sagittal balance and cervical lordosis. However, no study has been performed to explore the relationship between T1 sagittal angle and sagittal balance, and whether T1 sagittal angle could be used for osteotomy guidelines remains unknown. The aim of our study is to explore the relationship between T1 sagittal angle and sagittal balance, determine the predictors for T1 sagittal angle, and determine whether T1 sagittal angle could be used for osteotomy guidelines to restore sagittal balance. Medical records of healthy volunteers in our outpatient clinic from January 2014 to August 2015 were reviewed, and their standing full-spine lateral radiographs were evaluated. Demographic and radiological parameters were collected and analyzed, including age, gender, T1 sagittal angle, maxTK, maxLL, SS, PT, and PI. Correlation coefficients between T1 sagittal angle and other spinopelvic parameters were determined. In addition, multiple regression analysis was performed to establish predictive radiographic parameters for T1 sagittal angle as the primary contributors. A total of 119 healthy volunteers were recruited in our study with a mean age of 34.7 years. It was found that T1 sagittal angle was correlated with maxTK with very good significance (r = 0.697, P<0.001), maxLL with weak significance (r = 0.206, P = 0.024), SS with weak significance (r = 0.237, P = 0.009), PI with very weak significance (r = 0.189, P = 0.039), SVA with moderate significance (r = 0.445, P<0.001), TPA with weak significance (r = 0.207, P = 0.023), and T1SPI with weak significance (r = 0.309, P = 0.001). The result of multiple regression analysis showed that T1 sagittal angle could be predicted by using the following regression equation: T1 sagittal angle = 0.6 * maxTK-0.2 * maxLL + 8. In the healthy population, T1 sagittal angle could be considered as a useful parameter for sagittal balance; however, it could not be thoroughly replaced for SVA. maxTK was the primary contributor to T1 sagittal angle. According to this equation, we could restore sagittal balance by surgically changing thoracic kyphosis and lumbar lordosis, which could serve as a guideline for osteotomy.

Dataset Information

Relationship between the Condylion-Gonion-Menton Angle and Dentoalveolar Heights.

Publications

Relationship between the Condylion-Gonion-Menton Angle and Dentoalveolar Heights.

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