Ontology highlight
ABSTRACT:
SUBMITTER: Pokharel P
PROVIDER: S-EPMC7246781 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Pokharel Pravil P Díaz Juan Manuel JM Bessaiah Hicham H Houle Sébastien S Guerrero-Barrera Alma Lilián AL Dozois Charles M CM
International journal of molecular sciences 20200426 9
TagB, TagC (<i>t</i>andem <i>a</i>utotransporter <i>g</i>enes <i>B</i> and <i>C</i>), and Sha (<i>S</i>erine-protease <i>h</i>emagglutinin <i>a</i>utotransporter) are recently described members of the SPATE (serine protease autotransporters of <i>Enterobacteriaceae</i>) family. These SPATEs can cause cytopathic effects on bladder cells and contribute to urinary tract infection in a mouse model. Bladder epithelial cells form an important barrier in the urinary tract. Some SPATEs produced by patho ...[more]