Ontology highlight
ABSTRACT:
SUBMITTER: Giudice V
PROVIDER: S-EPMC7246934 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20200504 9
Aptamers or chemical antibodies are single-stranded DNA or RNA oligonucleotides that bind proteins and small molecules with high affinity and specificity by recognizing tertiary or quaternary structures as antibodies. Aptamers can be easily produced in vitro through a process known as systemic evolution of ligands by exponential enrichment (SELEX) or a cell-based SELEX procedure. Aptamers and modified aptamers, such as slow, off-rate, modified aptamers (SOMAmers), can bind to target molecules wi ...[more]