Identification of lysine acetylome in cervical cancer by label-free quantitative proteomics.
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ABSTRACT:
SUBMITTER: Zhang L
PROVIDER: S-EPMC7247262 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Identification of lysine acetylome in cervical cancer by label-free quantitative proteomics.
Zhang Lu L Wang Wanyue W Zhang Shanqiang S Wang Yuxin Y Guo Weikang W Liu Yunduo Y Wang Yaoxian Y Zhang Yunyan Y
Cancer cell international 20200524
<h4>Background</h4>Lysine acetylation is a post-translational modification that regulates a diversity of biological processes, including cancer development.<h4>Methods</h4>Here, we performed the quantitative acetylproteomic analysis of three primary cervical cancer tissues and corresponding adjacent normal tissues by using the label-free proteomics approach.<h4>Results</h4>We identified a total of 928 lysine acetylation sites from 1547 proteins, in which 495 lysine acetylation sites correspondin ...[more]
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