Digital PCR: A Reliable Tool for Analyzing and Monitoring Hematologic Malignancies.
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ABSTRACT:
SUBMITTER: Coccaro N
PROVIDER: S-EPMC7247671 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
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Digital PCR: A Reliable Tool for Analyzing and Monitoring Hematologic Malignancies.
Coccaro Nicoletta N Tota Giuseppina G Anelli Luisa L Zagaria Antonella A Specchia Giorgina G Albano Francesco F
International journal of molecular sciences 20200429 9
The digital polymerase chain reaction (dPCR) is considered to be the third-generation polymerase chain reaction (PCR), as it yields direct, absolute and precise measures of target sequences. dPCR has proven particularly useful for the accurate detection and quantification of low-abundance nucleic acids, highlighting its advantages in cancer diagnosis and in predicting recurrence and monitoring minimal residual disease, mostly coupled with next generation sequencing. In the last few years, a seri ...[more]
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