Ontology highlight
ABSTRACT:
SUBMITTER: Desantis V
PROVIDER: S-EPMC7247691 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Desantis Vanessa V Saltarella Ilaria I Lamanuzzi Aurelia A Melaccio Assunta A Solimando Antonio Giovanni AG Mariggiò Maria Addolorata MA Racanelli Vito V Paradiso Angelo A Vacca Angelo A Frassanito Maria Antonia MA
International journal of molecular sciences 20200427 9
MicroRNAs (miRNAs, or miRs) are single-strand short non-coding RNAs with a pivotal role in the regulation of physiological- or disease-associated cellular processes. They bind to target miRs modulating gene expression at post-transcriptional levels. Here, we present an overview of miRs deregulation in the pathogenesis of multiple myeloma (MM), and discuss the potential use of miRs/nanocarriers association in clinic. Since miRs can act as oncogenes or tumor suppressors, strategies based on their ...[more]