Association of cardiovascular diseases with milk intake among general Chinese adults.

ABSTRACT: BACKGROUND:The association of milk intake with cardiovascular disease (CVD) and cause-specific mortality remained controversial and evidence among the Chinese population was limited. We aimed to study the relationship between milk intake and CVDs among general Chinese adults. METHODS:A total of 104,957 participants received questionnaire survey. Results of physical examination such as anthropometric measurements and biochemical tests during 2007 to 2008, demographic data and their information on milk intake were collected through standardized questionnaires. Cox proportional hazard regression models were used to calculate hazard ratios (HRs) and their corresponding 95% confidence intervals (CIs) of CVD incidence, cause-specific mortality and all-cause mortality related to milk intake. Restricted cubic splines (RCSs) were applied to examine dose-response associations. RESULTS:Among the 91,757 participants with a median follow-up period of 5.8 years, we documented 3877 CVD cases and 4091 all-cause deaths. Compared with participants who never consumed milk, the multivariate-adjusted HRs (95% CIs) of CVD incidence for 1 to 150?g/day, 151 to 299?g/day, and ?300?g/day were 0.94 (0.86-1.03) (P?>?0.05), 0.77 (0.66-0.89) (P?

SUBMITTER: Wang XY 

PROVIDER: S-EPMC7249710 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature