Ontology highlight
ABSTRACT:
SUBMITTER: Lee AH
PROVIDER: S-EPMC7250846 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Lee Amy H AH Ghosh Deepraj D Quach Nhat N Schroeder Devin D Dawson Michelle R MR
Scientific reports 20200526 1
Exosomes are cell-secreted microvesicles that play important roles in epithelial ovarian cancer (EOC) progression, as they are constantly secreted into ascites fluids. While cells spontaneously release exosomes, alterations in intracellular calcium or extracellular pH can release additional exosomes. Yet, little is known about how these exosomes compare to those that are continuously released without stimulation and how they mediate cellular activities important in cancer progression. Here, we d ...[more]