Early administration of ritonavir-boosted lopinavir could prevent severe COVID-19.

ABSTRACT: No specific treatment against SARS-CoV-2 is available after 6 months of COVID-19 worldwide outbreak Antivirals could decrease the viral load and reduce direct and indirect damages of SARSCoV-2 infection Ritonavir-bosted lopinavir is effective against SARS-CoV-2 in vitro Sequential virological and pharmacological monitoring helped to understand the efficacy of ritonavir-boosted lopinavir in a SARS-CoV-2 infected patient Ritonavir-boosted lopinavir could be proposed as early treatment for SARS-CoV-2 infection.

SUBMITTER: Klement-Frutos E 

PROVIDER: S-EPMC7251410 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature