Fuling-Guizhi Herb Pair in Coronary Heart Disease: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation.
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ABSTRACT:
SUBMITTER: Duan B
PROVIDER: S-EPMC7251461 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
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Fuling-Guizhi Herb Pair in Coronary Heart Disease: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation.
Duan Bailu B Han Lintao L Ming Shuping S Li JingJing J Wang Qiong Q Zhang Dongning D Tian Guangyu G Huang Fang F
Evidence-based complementary and alternative medicine : eCAM 20200517
The Fuling (<i>Poria cocos</i>)-Guizhi (<i>Cinnamomi ramulus</i>) herb pair (FGHP) is a commonly used traditional Chinese herbal formula with coronary heart disease (CHD) treatment potential. However, the mechanism of FGHP in the treatment of CHD was still unclear. In this study, the action targets and underlying mechanism of FGHP against CHD were successfully achieved by combined network pharmacology prediction with experimental verification. 76 common targets were screened out by overlapping t ...[more]
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