Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Liquid seal for compact micropiston actuation at the capillary tip.

ABSTRACT: Actuators at the tip of a submillimetric catheter could facilitate in vivo interventional procedures at cellular scales by enabling tissue biopsy and manipulation or supporting active micro-optics. However, the dominance of frictional forces at this scale makes classical mechanism problematic. Here, we report the design of a microscale piston, with a maximum dimension of 150 ?m, fabricated with two-photon lithography onto the tip of 140-?m-diameter capillaries. An oil drop method is used to create a seal between the piston and the cylinder that prevents any leakage below 185-mbar pressure difference while providing lubricated friction between moving parts. This piston generates forces that increase linearly with pressure up to 130 ?N without breaking the liquid seal. The practical value of the design is demonstrated with its integration with a microgripper that can grasp, move, and release 50-?m microspheres. Such a mechanism opens the way to micrometer-size catheter actuation.

SUBMITTER: Barbot A

PROVIDER: S-EPMC7253165 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Publications

Liquid seal for compact micropiston actuation at the capillary tip.

Barbot Antoine A Power Maura M Seichepine Florent F Yang Guang-Zhong GZ

Science advances 20200527 22

Actuators at the tip of a submillimetric catheter could facilitate in vivo interventional procedures at cellular scales by enabling tissue biopsy and manipulation or supporting active micro-optics. However, the dominance of frictional forces at this scale makes classical mechanism problematic. Here, we report the design of a microscale piston, with a maximum dimension of 150 μm, fabricated with two-photon lithography onto the tip of 140-μm-diameter capillaries. An oil drop method is used to crea ...[more]

PMID: 32518828

Similar Datasets

Compact Thermal Actuation by Water and Flexible Hydrophobic Nanopore.

Project description:Efficient and compact energy conversion is at the heart of the sustainable development of humanity. In this work it is demonstrated that hydrophobic flexible nanoporous materials can be used for thermal-to-mechanical energy conversion when coupled with water. In particular, a reversible nonhysteretic wetting-drying (contraction-expansion) cycle provoked by periodic temperature fluctuations was realized for water and a superhydrophobic nanoporous Cu2(tebpz) MOF (tebpz = 3,3',5,5'-tetraethyl-4,4'-bipyrazolate). A thermal-to-mechanical conversion efficiency of ∼30% was directly recorded by high-precision PVT-calorimetry, while the operational cycle was confirmed by in operando neutron scattering. The obtained results provide an alternative approach for compact energy conversion exploiting solid-liquid interfacial energy in nanoscopic flexible heterogeneous systems.

| S-EPMC10537034 | biostudies-literature

Tip-multi-breaking in Capillary Microfluidic Devices.

Project description:We report tip-multi-breaking (TMB) mode of droplet breakup in capillary microfluidic devices. This new mode appears in a region embraced by Cai = 0 and lg(Cai) = -8.371(Ca0)?-7.36 with Ca0 varying from 0.35 to 0.63 on the Cai -?Ca0 phase diagram, Cai and Ca0 being the capillary numbers of inner and outer fluids, respectively. The mode is featured with a periodic, constant-speed thinning of the inner liquid tip and periodic formation of a sequence of droplets. The droplet number n in a sequence is determined by and increases with outer phase capillary number, and varies from two to over ten. The distribution of both pinch-off time and size of the droplets in a sequence is a geometric progression of common ratio that depends exclusively on and increases monotonically with the droplet number from its minimum value of 0.5 at n = 2 to its maximum value of 1 as n tends to infinity. These features can help identify the unique geometric morphology of droplet clusters and make them promising candidates for encryption and anti-fake identification.

| S-EPMC4468424 | biostudies-literature

Electrocapillary Actuation of Liquid Metal in Microchannels.

Project description:Controllable deformation of liquid metal by electrocapillary actuation (ECA) is empirically characterized in fluidic channels at the sub-millimeter-length scale. In 100-µm-deep channels of varying widths, the Galinstan liquid metal could move at velocities of more than 40 mm/s. The liquid metal could extend more than 2.5 mm into the channels at an electrocapillary actuation voltage of 3 V DC. The dynamic behavior of the liquid metal as it moves in the microchannels is described. These results are useful for designing microsystems that use liquid metal as a functional material.

| S-EPMC9032191 | biostudies-literature

An Underwater Robotic Manipulator with Soft Bladders and Compact Depth-Independent Actuation.

Project description:An underwater manipulator is essential for underwater robotic sampling and other service operations. Conventional rigid body underwater manipulators generally required substantial size and weight, leading to hindered general applications. Pioneering soft robotic underwater manipulators have defied this by offering dexterous and lightweight arms and grippers, but still requiring substantial actuation and control components to withstand the water pressure and achieving the desired dynamic performance. In this work, we propose a novel approach to underwater manipulator design and control, exploiting the unique characteristics of soft robots, with a hybrid structure (rigid frame+soft actuator) for improved rigidity and force output, a uniform actuator design allowing one compact hydraulic actuation system to drive all actuators, and a novel fully customizable soft bladder design that improves performances in multiple areas: (1) force output of the actuator is decoupled from the working depth, enabling wide working ranges; (2) all actuators are connected to the main hydraulic line without actuator-specific control loop, resulting in a very compact actuation system especially for high-dexterity cases; (3) dynamic responses were improved significantly compared with the counter system without bladder. A prototype soft manipulator with 4-DOFs, dual bladders, and 15 N payload was developed; the entire system (including actuation, control, and batteries) could be mounted onto a consumer-grade remotely operated vehicle, with depth-independent performances validated by various laboratory and field test results across various climatic and hydrographic conditions. Analytical models and validations of the proposed soft bladder design were also presented as a guideline for other applications.

| S-EPMC7591381 | biostudies-literature

Optical Actuation of Nanoparticle-Loaded Liquid-Liquid Interfaces for Active Photonics.

Project description:Liquid-liquid interfaces hold the potential to serve as versatile platforms for dynamic processes, due to their inherent fluidity and capacity to accommodate surface-active materials. This study explores laser-driven actuation of liquid-liquid interfaces with and without loading of gold nanoparticles and further exploits the laser-actuated interfaces with nanoparticles for tunable photonics. Upon laser exposure, gold nanoparticles were rearranged along the interface, enabling the reconfigurable, small-aperture modulation of light transmission and the tunable lensing effect. Adapting the principles of optical and optothermal tweezers, we interpreted the underlying mechanisms of actuation and modulation as a synergy of optomechanical and optothermal effects. Our findings provide an analytical framework for understanding microscopic interfacial behaviors, contributing to potential applications in tunable photonics and interfacial material engineering.

| S-EPMC11299852 | biostudies-literature

Euler force actuation mechanism for siphon valving in compact disk-like microfluidic chips.

Project description:Based on the Euler force induced by the acceleration of compact disk (CD)-like microfluidic chip, this paper presents a novel actuation mechanism for siphon valving. At the preliminary stage of acceleration, the Euler force in the tangential direction of CD-like chip takes the primary place compared with the centrifugal force to function as the actuation of the flow, which fills the siphon and actuates the siphon valving. The Euler force actuation mechanism is demonstrated by the numerical solution of the phase-field based mathematical model for the flow in siphon valve. In addition, experimental validation is implemented in the polymethylmethacrylate-based CD-like microfluidic chip manufactured using CO2 laser engraving technique. To prove the application of the proposed Euler force actuation mechanism, whole blood separation and plasma extraction has been conducted using the Euler force actuated siphon valving. The newly introduced actuation mechanism overcomes the dependence on hydrophilic capillary filling of siphon by avoiding external manipulation or surface treatments of polymeric material. The sacrifice for highly integrated processing in pneumatic pumping technique is also prevented by excluding the volume-occupied compressed air chamber.

| S-EPMC3977750 | biostudies-literature

Design and Validation of a Partial-Assist Knee Orthosis with Compact, Backdrivable Actuation.

Project description:This paper presents the mechatronic design and initial validation of a partial-assist knee orthosis for individuals with musculoskeletal disorders, e.g., knee osteoarthritis and lower back pain. This orthosis utilizes a quasi-direct drive actuator with a low-ratio transmission (7:1) to greatly reduce the reflected inertia for high backdrivability. To provide meaningful assistance, a custom Brushless DC (BLDC) motor is designed with encapsulated windings to improve the motor's thermal environment and thus its continuous torque output. The 2.69 kg orthosis is constructed from all custom-made components with a high package factor for lighter weight and a more compact size. The combination of compactness, backdrivability, and torque output enables the orthosis to provide partial assistance without obstructing the natural movement of the user. Several benchtop tests verify the actuator's capabilities, and a human subject experiment demonstrates reduced quadriceps muscle activation when assisted during a repetitive lifting and lowering task.

| S-EPMC6684309 | biostudies-literature

Magnetic Actuation of Drops and Liquid Marbles Using a Deformable Paramagnetic Liquid Substrate.

Project description:The magnetic actuation of deposited drops has mainly relied on volume forces exerted on the liquid to be transported, which is poorly efficient with conventional diamagnetic liquids such as water and oil, unless magnetosensitive particles are added. Herein, we describe a new and additive-free way to magnetically control the motion of discrete liquid entities. Our strategy consists of using a paramagnetic liquid as a deformable substrate to direct, using a magnet, the motion of various floating liquid entities, ranging from naked drops to liquid marbles. A broad variety of liquids, including diamagnetic (water, oil) and nonmagnetic ones, can be efficiently transported using the moderate magnetic field (ca. 50 mT) produced by a small permanent magnet. Complex trajectories can be achieved in a reliable manner and multiplexing potential is demonstrated through on-demand drop fusion. Our paramagnetofluidic method advantageously works without any complex equipment or electric power, in phase with the necessary development of robust and low-cost analytical and diagnostic fluidic devices.

| S-EPMC5836889 | biostudies-literature

Degradation-Induced Actuation in Oxidation-Responsive Liquid Crystal Elastomers.

Project description:Stimuli-responsive materials that exhibit a mechanical response to specific biological conditions are of considerable interest for responsive, implantable medical devices. Herein, we report the synthesis, processing and characterization of oxidation-responsive liquid crystal elastomers that demonstrate programmable shape changes in response to reactive oxygen species. Direct ink writing (DIW) is used to fabricate Liquid Crystal Elastomers (LCEs) with programmed molecular orientation and anisotropic mechanical properties. LCE structures were immersed in different media (oxidative, basic and saline) at body temperature to measure in vitro degradation. Oxidation-sensitive hydrophobic thioether linkages transition to hydrophilic sulfoxide and sulfone groups. The introduction of these polar moieties brings about anisotropic swelling of the polymer network in an aqueous environment, inducing complex shape changes. 3D-printed uniaxial strips exhibit 8% contraction along the nematic director and 16% orthogonal expansion in oxidative media, while printed LCEs azimuthally deform into cones 19 times their original thickness. Ultimately, these LCEs degrade completely. In contrast, LCEs subjected to basic and saline solutions showed no apparent response. These oxidation-responsive LCEs with programmable shape changes may enable a wide range of applications in target specific drug delivery systems and other diagnostic and therapeutic tools.

| S-EPMC8086701 | biostudies-literature

Self-sustained actuation from heat dissipation in liquid crystal polymer networks.

Project description:Liquid crystal polymer networks (LCNs) lead the research geared toward macroscopic motion of materials. These actuators are molecularly programed to adapt their shape in response to external stimuli. Non-photo-responsive thin films of LCNs covered with heat absorbers (e.g., graphene or ink) are shown to continuously oscillate when exposed to light. The motion is governed by the heat dissipated at the film surface and the anisotropic thermal deformation of the network. The influence of the LC molecular alignment, the film thickness, and the LC matrix on the macroscopic motion is analyzed to probe the limits of the system. The insights gained from these experiments provide not only guidelines to create actuators by photo-thermal or pure photo-effects but also a simple method to generate mechanical oscillators for soft robotics and automated systems. © 2018 The Authors. Journal of Polymer Science Part A: Polymer Chemistry Published by Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 1331-1336.

| S-EPMC6001434 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data