Ontology highlight
ABSTRACT:
SUBMITTER: Gardner A
PROVIDER: S-EPMC7253577 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Gardner Alycia A de Mingo Pulido Álvaro Á Ruffell Brian B
Frontiers in immunology 20200521
Despite significant advances in the field of cancer immunotherapy, the majority of patients still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have long been a focus of cancer immunotherapy due to their role in inducing protective adaptive immunity, but cancer vaccines have shown limited efficacy in the past. With the advent of immune checkpoint blockade and the ability to identify patient-specific neoantigens, new vaccines, and combinatorial therapies ar ...[more]