Ontology highlight
ABSTRACT:
SUBMITTER: Shen B
PROVIDER: S-EPMC7254001 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Cell 20200528 1
Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then trained a machine learning model using proteomic and metabolomic measurements from a training cohort of 18 non-severe and 13 severe patients. The model was validated using 10 independent patients, 7 of which were correctly classified. Targeted proteomics and metabolomics assays were employe ...[more]