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Loss to follow-up and opportunities for reengagement in HIV care in rural Mozambique: A prospective cohort study.


ABSTRACT: Patients lost to follow-up (LTFU) over the human immunodeficiency virus (HIV) cascade have poor clinical outcomes and contribute to onward HIV transmission. We assessed true care outcomes and factors associated with successful reengagement in patients LTFU in southern Mozambique.Newly diagnosed HIV-positive adults were consecutively recruited in the Manhiça District. Patients LTFU within 12 months after HIV diagnosis were visited at home from June 2015 to July 2016 and interviewed for ascertainment of outcomes and reasons for LTFU. Factors associated with reengagement in care within 90 days after the home visit were analyzed by Cox proportional hazards model.Among 1122 newly HIV-diagnosed adults, 691 (61.6%) were identified as LTFU. Of those, 557 (80.6%) were approached at their homes and 321 (57.6%) found at home. Over 50% had died or migrated, 10% had been misclassified as LTFU, and 252 (78.5%) were interviewed. Following the visit, 79 (31.3%) reengaged in care. Having registered in care and a shorter time between LTFU and visit were associated with reengagement in multivariate analyses: adjusted hazards ratio of 3.54 [95% confidence interval (CI): 1.81-6.92; P?

SUBMITTER: Fuente-Soro L 

PROVIDER: S-EPMC7254184 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Loss to follow-up and opportunities for reengagement in HIV care in rural Mozambique: A prospective cohort study.

Fuente-Soro Laura L   López-Varela Elisa E   Augusto Orvalho O   Bernardo Edson Luis EL   Sacoor Charfudin C   Nhacolo Ariel A   Ruiz-Castillo Paula P   Alfredo Charity C   Karajeanes Esmeralda E   Vaz Paula P   Naniche Denise D  

Medicine 20200501 20


Patients lost to follow-up (LTFU) over the human immunodeficiency virus (HIV) cascade have poor clinical outcomes and contribute to onward HIV transmission. We assessed true care outcomes and factors associated with successful reengagement in patients LTFU in southern Mozambique.Newly diagnosed HIV-positive adults were consecutively recruited in the Manhiça District. Patients LTFU within 12 months after HIV diagnosis were visited at home from June 2015 to July 2016 and interviewed for ascertainm  ...[more]

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