Soluble PD-L1: a potential immune marker for HIV-1 infection and virological failure.
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ABSTRACT:
SUBMITTER: Avendano-Ortiz J
PROVIDER: S-EPMC7254573 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
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Soluble PD-L1: a potential immune marker for HIV-1 infection and virological failure.
Avendaño-Ortiz José J Rubio-Garrido Marina M Lozano-Rodríguez Roberto R Del Romero Jorge J Rodríguez Carmen C Moreno Santiago S Aguirre Luis A LA Holguín África Á López-Collazo Eduardo E
Medicine 20200501 20
Despite viral control, basal chronic inflammation and its related comorbidities remain unsolved problems among HIV-infected individuals. Soluble factors derived from myeloid cells have emerged as potent markers associated with HIV-related comorbidities and mortality. In the present report, we explored the relationship between soluble programmed death-ligand 1 (sPD-L1) and HIV-1 infection, antiretroviral therapy (ART), CD4/CD8 ratio, viral load (VL), and sexually transmitted coinfections.A prospe ...[more]
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