Ontology highlight
ABSTRACT:
SUBMITTER: Clatot F
PROVIDER: S-EPMC7254698 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Clatot Florian F Perdrix Anne A Beaussire Ludivine L Lequesne Justine J Lévy Christelle C Emile George G Bubenheim Michael M Lacaille Sigrid S Calbrix Céline C Augusto Laetitia L Guillemet Cécile C Alexandru Cristina C Fontanilles Maxime M Sefrioui David D Burel Lucie L Guénot Sabine S Richard Doriane D Sarafan-Vasseur Nasrin N Di Fiore Frédéric F
Breast cancer research : BCR 20200528 1
<h4>Background</h4>Endocrine therapy is recommended as a first-line treatment for hormone receptor-positive metastatic breast cancer (HR+MBC) patients. No biomarker has been validated to predict tumor progression in that setting. We aimed to prospectively compare the risk of early progression according to circulating ESR1 mutations, CA-15.3, and circulating cell-free DNA in MBC patients treated with a first-line aromatase inhibitor (AI).<h4>Methods</h4>Patients with MBC treated with a first-line ...[more]