Ontology highlight
ABSTRACT:
SUBMITTER: Seatla KK
PROVIDER: S-EPMC7255068 | biostudies-literature | 2018 Aug
REPOSITORIES: biostudies-literature
Seatla Kaelo K KK Avalos Ava A Moyo Sikhulile S Mine Madisa M Diphoko Thabo T Mosepele Mosepele M Gaolatlhe Tendani T Rowley Christopher F CF Ramaabya Dinah D Jarvis Joseph N JN Kasvosve Ishmael I Gaseitsiwe Simani S
AIDS (London, England) 20180801 13
: There are limited data on the effectiveness of dolutegravir (DTG)-based combination antiretroviral therapy (ART) in real-life settings in southern Africa where HIV-1 subtype C predominates. We report a patient infected with HIV-1 subtype C on DTG-based ART previously exposed to raltegravir who developed multidrug resistance mutations to four antiretroviral classes. There is need for drug resistance monitoring and clinical vigilance to ensure effectiveness of HIV treatment programs even in the ...[more]