Ontology highlight
ABSTRACT:
SUBMITTER: Martens C
PROVIDER: S-EPMC7255514 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20200325 6
Integral membrane proteins (IMPs) control countless fundamental biological processes and constitute the majority of drug targets. For this reason, uncovering their molecular mechanism of action has long been an intense field of research. They are, however, notoriously difficult to work with, mainly due to their localization within the heterogeneous of environment of the biological membrane and the instability once extracted from the lipid bilayer. High-resolution structures have unveiled many me ...[more]