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Lithium and coronaviral infections. A scoping review.


ABSTRACT: The current rapid spread of the novel coronavirus (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) calls for a rapid response from the research community. Lithium is widely used to treat bipolar disorder, but has been shown to exhibit antiviral activity. This brief review took a systematic approach to identify six in vitro studies reporting on the influence of lithium on coronaviral infections. We propose mechanistic investigation of the influence of lithium - alone and with chloroquine - on the SARS-CoV-2 infection.

SUBMITTER: Nowak JK 

PROVIDER: S-EPMC7255895 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Lithium and coronaviral infections. A scoping review.

Nowak Jan K JK   Walkowiak Jarosław J  

F1000Research 20200207


The current rapid spread of the novel coronavirus (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) calls for a rapid response from the research community. Lithium is widely used to treat bipolar disorder, but has been shown to exhibit antiviral activity. This brief review took a systematic approach to identify six <i>in vitro</i> studies reporting on the influence of lithium on coronaviral infections. We propose mechanistic investigation of the influence of lithium - alone and with chlor  ...[more]

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