Ontology highlight
ABSTRACT:
SUBMITTER: Mpendo J
PROVIDER: S-EPMC7259687 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Mpendo Juliet J Mutua Gaudensia G Nanvubya Annet A Anzala Omu O Nyombayire Julien J Karita Etienne E Dally Len L Hannaman Drew D Price Matt M Fast Patricia E PE Priddy Frances F Gelderblom Huub C HC Hills Nancy K NK
PloS one 20200529 5
<h4>Introduction</h4>Intramuscular electroporation (IM/EP) is a vaccine delivery technique that improves the immunogenicity of DNA vaccines. We evaluated the acceptability and tolerability of electroporation among healthy African study participants.<h4>Methods</h4>Forty-five participants were administered a DNA vaccine (HIV-MAG) or placebo by electroporation at three visits occurring at four week-intervals. At the end of each visit, participants were asked to rate pain at four times: (1) when th ...[more]