Ontology highlight
ABSTRACT:
SUBMITTER: Wong WM
PROVIDER: S-EPMC7259934 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Wong Wen Mai WM Cao Jie J Zhang Xingjian X Doyle Wayne I WI Mercado Luis L LL Gautron Laurent L Meeks Julian P JP
Science advances 20200529 22
The mouse accessory olfactory system (AOS) supports social and reproductive behavior through the sensation of environmental chemosignals. A growing number of excreted steroids have been shown to be potent AOS cues, including bile acids (BAs) found in feces. As is still the case with most AOS ligands, the specific receptors used by vomeronasal sensory neurons (VSNs) to detect BAs remain unknown. To identify VSN BA receptors, we first performed a deep analysis of VSN BA tuning using volumetric GCa ...[more]