Pulmonary delivery of nanostructured lipid carriers for effective repurposing of salinomycin as an antiviral agent.
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ABSTRACT:
SUBMITTER: Pindiprolu SKSS
PROVIDER: S-EPMC7260485 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Pulmonary delivery of nanostructured lipid carriers for effective repurposing of salinomycin as an antiviral agent.
Pindiprolu Sai Kiran S S SKSS Kumar Chirravuri S Phani CSP Kumar Golla Venu Sampath VS P Likitha L K Shreyas Chandra SC S K Esub Basha EB R K Ramachandra R
Medical hypotheses 20200530
Coronavirus disease outbreak caused a severe public health burden all over the world. Salinomycin (SAL) is a broad-spectrum antibiotic that had drawn attention in selective targeting of cancer and viral infections. Recent drug screen identified SAL as a potent antiviral agent against SARS-CoV-2. In this hypothesis, we discuss the potential of pulmonary delivery of SAL using nanostructured lipid carriers (NLCs) against SARS-CoV-2. ...[more]
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