Ontology highlight
ABSTRACT:
SUBMITTER: Pflug C
PROVIDER: S-EPMC7261764 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Pflug Christina C Nienstedt Julie C JC Gulberti Alessandro A Müller Frank F Vettorazzi Eik E Koseki Jana-Christiane JC Niessen Almut A Flügel Till T Hidding Ute U Buhmann Carsten C Weiss Daniel D Gerloff Christian C Hamel Wolfgang W Moll Christian K E CKE Pötter-Nerger Monika M
Annals of clinical and translational neurology 20200408 5
<h4>Objectives</h4>Dysphagia is a frequent and highly relevant symptom in Parkinson's disease (PD) due to high associated morbidity and mortality. To compare the effect of simultaneous stimulation of the subthalamic nucleus (STN) and substantia nigra (SNr) with conventional STN-stimulation on swallowing function in Parkinson's disease.<h4>Methods</h4>In this controlled, randomized, double-blind, cross-over clinical trial, 15 PD patients were assessed with DBS switched off (STIM OFF), STN-DBS, ST ...[more]