Significance of Single-Nucleotide Variants in Long Intergenic Non-protein Coding RNAs.
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ABSTRACT:
SUBMITTER: Zou H
PROVIDER: S-EPMC7261909 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Significance of Single-Nucleotide Variants in Long Intergenic Non-protein Coding RNAs.
Zou Hecun H Wu Lan-Xiang LX Tan Lihong L Shang Fei-Fei FF Zhou Hong-Hao HH
Frontiers in cell and developmental biology 20200525
Single-nucleotide variants (SNVs) are the most common genetic variants and universally present in the human genome. Genome-wide association studies (GWASs) have identified a great number of disease or trait-associated variants, many of which are located in non-coding regions. Long intergenic non-protein coding RNAs (lincRNAs) are the major subtype of long non-coding RNAs; lincRNAs play crucial roles in various disorders and cellular models <i>via</i> multiple mechanisms. With rapid growth in the ...[more]
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2016-05-11 | PXD002465 | Pride