Ontology highlight
ABSTRACT:
SUBMITTER: Li Y
PROVIDER: S-EPMC7262922 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Li Yang Y Wang Hong-Chang HC Wang Jin-Shen JS Sun Bo B Li Le-Ping LP
FEBS open bio 20200507 6
Gastric cancer (GC) is a common tumor with a low 5-year survival rate. The chemokine receptor 4 (CXCR4) protein contributes to the progression and prognosis of GC, but the relationship between CXCR4 and immune infiltration, somatic copy number alteration (SCNA), tumor purity, tumor mutation burden (TMB), cytolytic activity (CYT), and drug sensitivity in GC is poorly understood. This study aimed to systematically explore the role of CXCR4 in GC. Microarray and RNA-seq data were collected from the ...[more]