Intervertebral Disc Repair: Current Concepts.

ABSTRACT:

Study design

Review article.

Objective

A review of the literature on current strategies utilized in intervertebral regeneration and repair efforts.

Methods

A review of the literature and analysis of the data to provide an updated review on current concepts of intervertebral disc repair and regeneration efforts.

Results

Multiple regenerative strategies for intervertebral disc regeneration are being employed to reduce pain and improve quality of life. Current promising strategies include molecular therapy, gene therapy, cell-based therapy, and augmentation with biomaterials. Multiple clinical trials studying biologic, cell-based, and scaffold-based injectable therapies are currently being investigated.

Conclusion

Low back pain due to intervertebral disc di

SUBMITTER: Ju DG 

PROVIDER: S-EPMC7263334 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature