The Long-Term Clinical and Endoscopic Outcomes of Cronkhite-Canada Syndrome.

ABSTRACT:

Introduction

The prognosis of Cronkhite-Canada syndrome (CCS) is considered poor. Despite the recent therapeutic improvements, the survival outcomes and prognostic factors have been less studied. This study aimed to investigate the long-term clinical and endoscopic outcomes of CCS.

Methods

Thirty-one patients diagnosed since 1999 and followed up for over 6 months were included. Data regarding survival outcomes, clinical symptoms, endoscopic findings, and treatment were collected and analyzed. R (version 3.6.1) was used to perform the survival analyses.

Results

The median (interquartile range) follow-up time was 42.5 (19.5-85.8) months. The 5-year overall survival (OS) was 87.4%. The maximum gastric polyp size over 2 cm was associated with worse OS (Hazard ratio [HR]:

SUBMITTER: Liu S 

PROVIDER: S-EPMC7263663 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature