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COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine.


ABSTRACT: Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab, after immunosuppression reduction; the patient did not require mechanical ventilation. During the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, transplant clinicians should be readily informed about new cases of COVID-19 pneumonia in solid organ transplant recipients, with focus on therapeutic strategies employed and their outcome.

SUBMITTER: Fontana F 

PROVIDER: S-EPMC7264495 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine.

Fontana Francesco F   Alfano Gaetano G   Mori Giacomo G   Amurri Alessio A   Tei Lorenzo L   Ballestri Marco M   Leonelli Marco M   Facchini Francesca F   Damiano Francesca F   Magistroni Riccardo R   Cappelli Gianni G  

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20200513 7


Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab, after immunosuppression reduction; the patient did no  ...[more]

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